Comprehensive Analysis of Parasite Biology

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À propos

Written and edited by experts in the field, this book brings together the current state of the art in phenotypic and rational, target-based approaches to drug discovery against pathogenic protozoa. The chapters focus particularly on virtual compounds and high throughput screening, natural products, computer-assisted drug design, structure-based drug design, mechanism of action identification, and pathway modelling. Furthermore, state-of the art "omics" technologies are described and currently studied enzymatic drug targets are discussed. Mathematical, systems biology-based approaches are introduced as new methodologies for dissecting complex aspects of pathogen survival mechanisms and for target identification. In addition, recently developed anti-parasitic agents targeting particular pathways, which serve as lead compounds for further drug development, are presented.

  • Auteur(s)

    Sylke Muller, Rachel Cerdan, Ovidiu Radulescu

  • Éditeur

    Wiley-Blackwell

  • Date de parution

    19/07/2016

  • EAN

    9783527694112

  • Disponibilité

    Disponible

  • Nombre de pages

    576 Pages

  • Action copier/coller

    Non

  • Action imprimer

    Dans le cadre de la copie privée

  • Nb pages imprimables

    576

  • Partage

    Dans le cadre de la copie privée

  • Nb Partage

    6 appareils

  • Poids

    13 097 Ko

  • Distributeur

    Numilog

  • Diffuseur

    Numilog

  • Entrepôt

    Numilog

  • Support principal

    ebook (ePub)

  • Ref catalogue

    1012626

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